| 发明名称 |
Molecular toxicology modeling |
| 摘要 |
The present invention is based on the elucidation of the global changes in gene expression and the identification of toxicity markers in tissues or cells exposed to a known toxin. The genes may be used as toxicity markers in drug screening and toxicity assays. The invention includes a database of genes characterized by toxin-induced differential expression that is designed for use with microarrays and other solid-phase probes.
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| 申请公布号 |
US2002119462(A1) |
申请公布日期 |
2002.08.29 |
| 申请号 |
US20010917800 |
申请日期 |
2001.07.31 |
| 申请人 |
MENDRICK DONNA L.;PORTER MARK W.;JOHNSON KORY R.;CASTLE ARTHUR L.;ELASHOFF MICHAEL R. |
发明人 |
MENDRICK DONNA L.;PORTER MARK W.;JOHNSON KORY R.;CASTLE ARTHUR L.;ELASHOFF MICHAEL R. |
| 分类号 |
C12N15/09;C12Q1/02;C12Q1/68;G06F19/28;(IPC1-7):C12Q1/68;G06F19/00;G01N33/48;G01N33/50 |
主分类号 |
C12N15/09 |
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