发明名称 |
COASTER, A HUMAN COACTIVATOR OF STEROID RECEPTORS |
摘要 |
The invention provides a protein having an amino acid sequence as in SEQ ID 7, 8, 11 or 12, similar proteins, naturally occurring variants and homologous functional equivalents thereof, as well as the use of a polynucleotide encoding such protein, for use in an assay and for use in a method of modulation of transcriptional activity promoted by a responsive nuclear receptor and a coactivator, which coactivator is the mentioned protein and is named COASTER, and which nuclear receptor is preferrably a steroid receptor. |
申请公布号 |
WO0216426(A3) |
申请公布日期 |
2002.08.29 |
申请号 |
WO2001EP09499 |
申请日期 |
2001.08.16 |
申请人 |
AKZO NOBEL N.V.;DECHERING, KOEN, JACOB;MOSSELMAN, SIETSE |
发明人 |
DECHERING, KOEN, JACOB;MOSSELMAN, SIETSE |
分类号 |
C12N15/09;A61K35/12;A61K38/00;A61P5/24;A61P9/00;A61P15/12;A61P15/16;A61P15/18;C07K14/47;C12Q1/02;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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