The present invention provides cationic polymers that include a primary amine and a targeting group covalently bound to the primary amine, wherein the targeting group targets a cell of interest by interacting with the surface of the cell. The invention also provides molecular complexes that include a polyethyleneimine and a targeting group covalently bound to a primary amine of the polyethyleneimine, and a biologically active compound. The invention further provides methods for delivering a biologically active compound to a vertebrate cell.
申请公布号
WO0189579(A3)
申请公布日期
2002.08.29
申请号
WO2001US16015
申请日期
2001.05.19
申请人
REGENTS OF THE UNIVERSITY OF MINNESOTA;STEER, CLIFFORD, J.;KREN, BETSY, T.;LINEHAN-STIEERS, CHERYLE;MCIVOR, R., SCOTT
发明人
STEER, CLIFFORD, J.;KREN, BETSY, T.;LINEHAN-STIEERS, CHERYLE;MCIVOR, R., SCOTT