BIOCONJUGATES OF NANOPARTICLES AS RADIOPHARMACEUTICALS

摘要

A bioconjugate including a nonoparticle covatently linked to a biological vector molecule. The nanoparticle is a generally radiocative metal ion and most typically a metal oxide. The biological vector molecule is typically a monoclonal antibody or fragment of a monoclonal antibody or a peptide having a known affinity to cancer cells. One or more additional, different biological moieties may be covalently linked to the nanoparticle in addition to the biological moieties may be covalently activity. The bioconjugate of the present invention has utility as an effective radiopharmaceutical to deliver a radiolabel in tumor treatment.