The present invention is directed to a synthetic nucleic acid sequence which encodes a protein wherein at least one non-common codon or less-common codon is replaced by a common codon. The synthetic nucleic acid sequence can include a continuous stretch of at least 90 codons all of which are common codons.
申请公布号
WO02064799(A2)
申请公布日期
2002.08.22
申请号
WO2001US42655
申请日期
2001.10.11
申请人
TRANSKARYOTIC THERAPIES, INC.;SELDON, RICHARD, F.;MILLER, ALLAN, M.;TRECO, DOUGLAS, S.
发明人
SELDON, RICHARD, F.;MILLER, ALLAN, M.;TRECO, DOUGLAS, S.
