发明名称 |
NEUROTHERAPEUTIC USE OF CARBOXYPEPTIDASE INHIBITORS |
摘要 |
Administration of inhibitors of carboxypeptidase E provides significant neurotropic effects in warm-blooded vertebrates evidenced inter alia by anxiolytic and anti-aggressive behavior and enhanced cognition. Certain beta -Lactam antibiotics, most significantly, certain 1-oxa-1-dethia cephems with blood brain barrier transport, exhibit potent therapeutic neurologic activity. |
申请公布号 |
WO02064087(A2) |
申请公布日期 |
2002.08.22 |
申请号 |
WO2002US04260 |
申请日期 |
2002.02.12 |
申请人 |
REVAAX PHARMACEUTICALS, LLC |
发明人 |
KOPPEL, GARY, A.;CHANEY, MICHAEL, O. |
分类号 |
A61K31/00;A61K31/197;A61K31/198;A61K31/395;A61K31/424;A61K31/43;A61K31/431;A61K31/4353;A61K31/5365;A61K31/5383;A61K31/545;A61K31/546;A61K45/06 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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