发明名称 Substituted (1,3-bis(cyclohexylmethyl)-1,2,3,6-tetrahydro-2,6-dioxo-9h-purin-8-yl) phenyl derivatives, their preparation and their use in the treatment of inflammatory conditions and immune disorders
摘要 The present invention provides a compound of formula (I)or a solvate thereof wherein:X is -O- or -NH-;Q is (-CH2-)p, (-CH=CH-)p, (-C=C-)p where p is an integer of from 0 to 4;R1 is hydrogen or methyl;R2 and R3 independently represent O or Sn is an integer of 1 to 50; andR is hydrogen or methyl.The present invention also provides pharmaceutical compositions and methods of treatment using the compounds of formula (I).
申请公布号 US6437124(B1) 申请公布日期 2002.08.20
申请号 US20010872546 申请日期 2001.06.01
申请人 SMITHKLINE BEECHAM CORPORATION 发明人 DALUGE SUSAN MARY;WOLBERG GERALD;LIVINGSTON DOUGLAS ALAN
分类号 A61K31/52;A61K31/522;A61P29/00;A61P29/02;A61P37/00;A61P37/02;A61P37/06;A61P43/00;C07D473/06;C07D473/20;C07D473/22;(IPC1-7):C07D473/06 主分类号 A61K31/52
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