发明名称 |
Substituted (1,3-bis(cyclohexylmethyl)-1,2,3,6-tetrahydro-2,6-dioxo-9h-purin-8-yl) phenyl derivatives, their preparation and their use in the treatment of inflammatory conditions and immune disorders |
摘要 |
The present invention provides a compound of formula (I)or a solvate thereof wherein:X is -O- or -NH-;Q is (-CH2-)p, (-CH=CH-)p, (-C=C-)p where p is an integer of from 0 to 4;R1 is hydrogen or methyl;R2 and R3 independently represent O or Sn is an integer of 1 to 50; andR is hydrogen or methyl.The present invention also provides pharmaceutical compositions and methods of treatment using the compounds of formula (I).
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申请公布号 |
US6437124(B1) |
申请公布日期 |
2002.08.20 |
申请号 |
US20010872546 |
申请日期 |
2001.06.01 |
申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
DALUGE SUSAN MARY;WOLBERG GERALD;LIVINGSTON DOUGLAS ALAN |
分类号 |
A61K31/52;A61K31/522;A61P29/00;A61P29/02;A61P37/00;A61P37/02;A61P37/06;A61P43/00;C07D473/06;C07D473/20;C07D473/22;(IPC1-7):C07D473/06 |
主分类号 |
A61K31/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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