发明名称 CARBOXYLIC ACID AMIDES, THEIR PRODUCTION AND THEIR USE AS DRUGS.
摘要 <p>The invention relates to carboxylic acid amides of formula (I), wherein R1 to R5, Ar, m and n are defined in Claim 1, their tautomers, their stereoisomers, their mixtures, their prodrugs and their salts, which exhibit valuable properties. The compounds of the above mentioned formula (I), wherein R5 represents a cyano group, are valuable intermediates for the production of other compounds of formula (I). The compounds of said formula (I), wherein R5 represents one of the amidino groups mentioned in Claim 1, exhibit valuable pharmacological properties, especially an antithrombotic property and a factor Xa-inhibitory property.</p>
申请公布号 MXPA02001329(A) 申请公布日期 2002.08.12
申请号 MX2002PA01329 申请日期 2000.08.02
申请人 BOEHRINGER INGELHEIM PHARMA KG 发明人 RIES, UWE
分类号 C07D295/18;A61K31/167;A61K31/18;A61K31/40;A61K31/4453;A61P7/02;A61P43/00;C07C257/18;C07C303/40;C07C311/21;C07C311/46;C07D207/12;C07D211/46;C07D213/68;C07D233/54;C07D295/135;C07D295/185;C07D295/192;(IPC1-7):A61K31/40;A61K31/416;C07D295/12 主分类号 C07D295/18
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