发明名称 Cdk4 AND/OR Cdk6 INHIBITOR INCLUDING BIARYLUREA COMPOUND OR ITS SALT AS ACTIVE INGREDIENT
摘要 PROBLEM TO BE SOLVED: To provide a Cdk4 and/or Cdk6 inhibitor or the like that is aimed at treating malignant tumor. SOLUTION: This Cdk4 and/or Cdk6 inhibitor includes a compound represented by formula (I) [wherein, Ar is a N-including heteroaromatic; X and Z are each C or the like; Y is CO or the like; R1 is H or the like; R2 and R3 are each H or the like; R4 and R5 are each H or the like ; and a partial structure (...) represents a single or double bond] or its salt as an active ingredient.
申请公布号 JP2002220338(A) 申请公布日期 2002.08.09
申请号 JP20010018755 申请日期 2001.01.26
申请人 BANYU PHARMACEUT CO LTD 发明人 HAYAMA TAKASHI;HAYASHI KYOKO;HONMA MITSUTAKA;TAKAHASHI IKUKO
分类号 C07D239/42;A61K31/407;A61K31/415;A61K31/4155;A61K31/424;A61K31/426;A61K31/428;A61K31/437;A61K31/4375;A61K31/44;A61K31/4402;A61K31/4409;A61K31/4418;A61K31/4427;A61K31/443;A61K31/4433;A61K31/4439;A61K31/444;A61K31/4523;A61K31/454;A61K31/496;A61K31/4965;A61K31/505;A61K31/506;A61K31/5365;A61K31/5377;A61K31/553;A61K31/695;A61P35/00;A61P43/00;C07D213/75;C07D213/79;C07D213/80;C07D213/82;C07D231/38;C07D231/52;C07D241/20;C07D277/20;C07D277/48;C07D277/82;C07D405/12;C07D409/12;C07D417/12;C07D453/02;C07D487/04;C07D498/04;C07D498/10;C07D519/00;(IPC1-7):A61K31/440;A61K31/440;A61K31/442;A61K31/452;A61K31/536;A61K31/537 主分类号 C07D239/42
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