COMPOUNDS REGULATING CELL PROLIFERATION AND DIFFERENTIATION

摘要

The invention provides compounds and methods for normalizing the proliferation and/or modulating differentiation and/or inducing the cell death of cells. In a preferred embodiment, the invention provides methods for inhibiting proliferation of hyper-proliferative cells, comprising contacting the cells with a composition comprising a growth inhibiting amount of one or more compounds selected from the group consisting of E20 (ID 141525); F12 (ID 120590); F16 (ID 274873); H10 (ID 120670); J6 (ID 120856); N12 (ID 215015); L4 (ID 121113); B15 (ID 217496) and QR, or derivatives or analogs thereof, or pharmaceutically acceptable salts thereof.