发明名称 |
METHOD FOR THE EVOLUTIONARY DESIGN OF BIOCHEMICAL REACTION NETWORKS |
摘要 |
The present invention relates to methods for achieving an optimal function of a biochemical reaction network. The methods can be performed in silico using a reconstruction of a biochemical reaction network of a cell an iterative optimization procedures. The methods can further include laboratory culturing steps to confirm and possibly expand the determinations made using the in silico</i> methods, and to produce a cultured cell, or population of cells, with optimal functions. The current invention includes computer systems and computer products including computer-readable program code for performing the in silico steps of the invention. |
申请公布号 |
WO02061115(A2) |
申请公布日期 |
2002.08.08 |
申请号 |
WO2002US02939 |
申请日期 |
2002.01.31 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
PALSSON, BERNHARD, O.;EDWARDS, JEREMY, S. |
分类号 |
C12N15/09;C12N1/15;C12N1/19;C12N1/20;C12N1/21;C12N5/10;G06F17/30;G06F19/12;G06F19/18 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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