| 摘要 |
The invention relates to medicine, and more specifically to pharmacology, and in particular to synthetic biologically active compounds of heterocyclic series, and it is designated mainly for use in medicine practice. The objective of the invention is obtaining new chemical substances possessing wide range of biological activities, including antiviral activity (regarding Herpes Simplex virus), immune stimulating activity (for the expense of inducing production of endogenic interferons in a body), and antichlamydial, hepatoprotective, antiaggregational, and antimicrobial activities. In other words, the objective of the invention is to synthesize new biologically active compounds that outperform known analogs in some characteristics and range of action. The proposed objective is achieved by synthesis of aryl- and heterylamides of carboalkoxysulfanilic acids of the general formula (1) <CHEM> where: R1 is taken from the group of aryls or heteryls; R2 is taken from the group of alkyls. General method of producing the claimed compounds and results of identification, a list of 42 compounds synthesized and tested, and experimental data on comparative testing their biological properties and toxicity are presented. 1 independ. and 42 depend. items of the formula, 9 tables, 10 ref. |
