| 摘要 |
The present invention relates to novel, non-peptidic small organic compounds having an affinity for cyclophilin (CyP)-type immunophilin proteins, and to pharmaceutical compositions comprising one or more of the said compounds. The invention further relates to the uses of these compounds and compositions for binding CyP-type proteins, inhibiting their peptidyl-prolyl isomerase activity, and for research, development, and therapeutic applications in a variety of medical disorders. |
| 申请人 |
GUILFORD PHARMACEUTICALS INC.;WU, YONG-QIAN;BELYAKOV, SERGEI;HAMILTON, GREGORY;LIMBURG, DAVID;STEINER, JOSEPH;VAAL, MARK;WEI, LING;WILKINSON, DOUGLAS |
发明人 |
WU, YONG-QIAN;BELYAKOV, SERGEI;HAMILTON, GREGORY;LIMBURG, DAVID;STEINER, JOSEPH;VAAL, MARK;WEI, LING;WILKINSON, DOUGLAS |
