| 摘要 |
PCT No. PCT/FI97/00388 Sec. 371 Date Feb. 19, 1998 Sec. 102(e) Date Feb. 19, 1998 PCT Filed Jun. 18, 1997 PCT Pub. No. WO97/48492 PCT Pub. Date Dec. 24, 1997The invention relates to a closure device and a method for performing an assay of a sample using the closure device. The closure device, mountable on the mouth of a test vessel, comprises a body part (1) with an axially passing cylindrical bore. The bore is covered at one end with an openable lid (7). The closure device further includes a plunger (3), slidably mounted in the bore for the formation of a sealed reagent storage chamber (9) in the space remaining between the closed lid and the plunger. The inner wall of the bore (2) is provided with at least one groove (4), whose depth is so deep as not to be within the reach of the outer diameter of the plunger (3). The groove extends from exterior end of the bore, over such a length as to maintain a gas flow communication between said reagent storage chamber (9) and the exterior end of the cylindrical bore when the plunger (3) is in a partially inserted position. In the assay method according to the invention, the reagent is added from the closure into the test vessel containing the sample. |
