发明名称 USE OF TRIFUNCTIONAL BISPECIFIC AND TRISPECIFIC ANTIBODIES FOR THE TREATMENT OF MALIGNANT ASCITES
摘要 The invention relates to the use of a pharmaceutical preparation, containing a trifunctional bispecific and/or trispecific antibody with the following properties: a) binding to a T-cell; b) binding to at least one antigen on a tumour cell, connected to malignant ascites and/or a pleural effusion; c) binding by means of the Fc component thereof (for bispecific antibodies), or by means of a third specificity (for trispecific antibodies) to Fc-receptor-positive cells to destroy the tumour cells in treatment of malignant ascites and/or a pleural effusion.
申请公布号 WO0220039(A3) 申请公布日期 2002.07.25
申请号 WO2001EP10184 申请日期 2001.09.04
申请人 LINDHOFER, HORST 发明人 LINDHOFER, HORST
分类号 A61K39/00;A61K39/395;A61P35/00;C07K16/28;C07K16/30;C07K16/32 主分类号 A61K39/00
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