发明名称 Recombinant adenoviruses containing an inducible promoter controlling a gene of viral origin
摘要 A recombinant adenovirus in which the expression of a nucleic acid sequence coding for at least one homologous or heterologous gene of viral origin is placed under the control of an inducible promoter, is disclosed. The use of such recombinant adenoviruses for preparing AAVs, and a complementary cell line and preparation method therefor, are also disclosed. Furthermore, pharmaceutical compositions containing such an adenovirus are disclosed.
申请公布号 US6420170(B1) 申请公布日期 2002.07.16
申请号 US19970981354 申请日期 1997.12.19
申请人 AVENTIS PHARMA S.A. 发明人 PERRICAUDET MICHEL;LATTA MARTINE;PROST EDOUARD;YEH PATRICE;ORSINI CéCILE;VIGNE EMMANUELLE
分类号 C12N15/09;A61K35/76;A61K48/00;C12N5/10;C12N7/00;C12N7/01;C12N15/63;C12N15/861;C12N15/864;(IPC1-7):C12N15/861 主分类号 C12N15/09
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