| 发明名称 |
METHOD OF IDENTIFYING PARTIAL ADENOSINE A1 RECEPTOR AGONISTS AND THEIR USE IN THE TREATMENT OF ARRHYTHMIAS |
| 摘要 |
The present invention provides a method for identifying partial adenosine A1 receptor, based on comparing the (35S)-GTP-gamma-S binding to G proteins induced by a candidate compound and by a full agonist. N6-heterocyclic-C8-modified adenosine derivates were identified, useful in treating arrhytmias.
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| 申请公布号 |
WO0140799(A3) |
申请公布日期 |
2002.07.11 |
| 申请号 |
WO2000US42430 |
申请日期 |
2000.12.01 |
| 申请人 |
CV THERAPEUTICS, INC.;BELARDINELLI, LUIZ;GAO, ZHENHAI |
发明人 |
BELARDINELLI, LUIZ;GAO, ZHENHAI |
| 分类号 |
C07H19/16;(IPC1-7):G01N33/68;A61K31/00;C07H19/00 |
主分类号 |
C07H19/16 |
| 代理机构 |
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