PROCESS FOR MANUFACTURE OF N-ALKOXY (OR ARYLOXY)CARBONYL ISOTHIOCYANATE DERIVATIVES IN THE PRESENCE OF N,N-DIALKYLARYLAMINE CATALYST ANDAQUEOUS SOLVENT

摘要

The present invention provides a process for making N-alkoxy(or aryloxy)carbonyl isothiocyanate derivatives by reacting a chloroformate with a thiocyanate, in the presence of an aqueous solvent and a catalytic amount of a N,N-dialkylarylamine, to produce a N-alkoxy(or aryloxy)carbonyl isothiocyanate intermediate product, wherein the intermediate product is converted to a N-alkoxy(or aryloxy)carbonyl isothiocyanate derivative in high yield and purity.