发明名称 METHODS AND COMPOSITIONS FOR TREATING PERIODONTAL DISEASE
摘要 <p>The present invention provides for a method for the treatment of alveolar bone loss due to periodontal disease in a subject in need of such treatment comprising administration of a therapeutically effective amount of an αvβ3 integrin receptor antagonist in combination with a therapeutically effective amount of a COX-2 inhibitor. Further, the present invention provides for pharmaceutical compositions useful in the methods of the present invention, as well as a method of manufacture of a medicament useful for treating the alveolar bone loss due to periodontal disease.</p>
申请公布号 WO2002053099(A2) 申请公布日期 2002.07.11
申请号 US2001049638 申请日期 2001.12.28
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