摘要 |
<p>The present invention concerns peptide nucleic acid (PNA) sequences, which are modified in order to obtain novel PNA molecules with enhanced properties. The peptide nucleic acid (PNA) oligomers are characterized in that the single units of the oligomer consists of different amino acid backbones selected from aminoethylglycine (aeg), aminoethylprolyl (aep), aminoethylpyrrolidine (pyr) or an amino acid more over is modified PNA conjugate of formula (I):Q - L - PNA (I) claimed, wherein L is a linker or a bond; Q is the peptide and PNA is the peptide nucleic acid oligomer.</p> |