| 发明名称 |
Anti-picornaviral ligands via a combinatorial computational and synthetic approach |
| 摘要 |
The present invention provides structure-based combinatorial libraries of compounds containing the functional group minima of picornaviruses including poliovirus and rhinovirus. The libraries can be used to screen for therapeutical antiviral compounds, e.g., anti-picornaviral capsid-binding compounds.
|
| 申请公布号 |
US6416762(B1) |
申请公布日期 |
2002.07.09 |
| 申请号 |
US19980210282 |
申请日期 |
1998.12.11 |
| 申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
JOSEPH-MCCARTHY DIANE M.;ISAACS LYLE D.;WHITESIDES GEORGE M.;KARPLUS MARTIN;HOGLE JAMES M.;CHEH JAMES LI-WEN |
| 分类号 |
A61K47/48;(IPC1-7):A61K39/125;C12P17/00;G01N33/543 |
主分类号 |
A61K47/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
