发明名称 |
Antibodies that bind to alpha2-antiplasmin crosslinked to fibrin which do not inhibit plasma alpha2-antiplasmin |
摘要 |
The present invention relates to a treatment for myocardial infarction and blood clots within a patient, and more specifically to a therapy which enhances clot lysis comprising administering to a patient an antibody directed to alpha2-antiplasmin crosslinked to fibrin (alpha2AP-FX) which does not inhibit plasma alpha2-antiplasmin (alpha2AP). The invention also relates to a treatment for enhancing clot lysis comprising administering an antibody directed toward alpha2-antiplasmin crosslinked to fibrin which does not inhibit plasma alpha2AP together with a thrombolytic agent.
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申请公布号 |
US2002086025(A1) |
申请公布日期 |
2002.07.04 |
申请号 |
US20010930307 |
申请日期 |
2001.08.16 |
申请人 |
REED GUY L.;HABER EDGAR;MATSUEDA GARY R. |
发明人 |
REED GUY L.;HABER EDGAR;MATSUEDA GARY R. |
分类号 |
A61K38/00;A61K38/49;A61K39/395;A61K45/06;C07K16/38;C07K16/40;C12P21/08;(IPC1-7):A61K39/00;A61K39/38;C07K1/00;C07K14/00;C07K17/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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