| 发明名称 |
ENTERICALLY COATED CYSTEAMINE, CYSTAMINE AND DERIVATIVES THEREOF |
| 摘要 |
The disclosure provides oral cysteamine and cystamine formulations useful for treating cystinosis and neurodegenerative diseases and disorders. The formulations provide controlled release compositions that improve quality of life and reduced side-effects. |
| 申请公布号 |
US2016331691(A1) |
申请公布日期 |
2016.11.17 |
| 申请号 |
US201615224414 |
申请日期 |
2016.07.29 |
| 申请人 |
The Regents of the University of California |
发明人 |
Dohil Ranjan;Schneider Jerry |
| 分类号 |
A61K9/28;A61K31/145 |
主分类号 |
A61K9/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising:
delayed and extended release enterically coated cysteamine bitartrate formulation comprising:
a core tablet comprising cysteamine bitartrate and a binder; andan enteric coating surrounding the core tablet, wherein the enteric coating releases the cysteamine bitartrate at a pH of 4.5 or greater and provides a Cmax of between 2-4 hours after administration. |
| 地址 |
Oakland CA US |
