发明名称 |
METHOD OF IDENTIFYING AGENTS THAT ALTER THE ACTIVITY OF THE PROMOTER SEQUENCE FOR CRF RECEPTOR 2-ALPHA |
摘要 |
A method for identifying agents that alter the activity of the promoter region of CRF2 alpha receptor is disclosed. In one embodiment, the method comprises the steps of (a) obtaining a cell line or organism, wherein the cell line or organism comprises a nucleic acid sequence encoding a promoter sequence of a heterologous CRF2 alpha receptor operably attached to a reporter gene and (b) introducing a test agent into the cell or transgenic animal and evaluating the expression of the reporter gene product compared to a control cell line or transgenic animal wherein the agent has not been introduced into the cell line or transgenic animal. |
申请公布号 |
WO0183563(A3) |
申请公布日期 |
2002.07.04 |
申请号 |
WO2001US13920 |
申请日期 |
2001.04.30 |
申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
KALIN, NED, H.;ROSEBOOM, PATRICK, H.;LANDRY, CHARLES, F.;NANDA, STEVEN, A. |
分类号 |
A01K67/027;A01K67/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/85;C12Q1/68;G01N33/15;G01N33/50;G01N33/567 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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