发明名称 Anilide derivative, production and use thereof
摘要 This invention is to provide a compound of the formula:wherein R1 is an optionally substituted 5- to 6-membered ring; W is a divalent group of the formula:wherein the ring A is an optionally substituted 5- to 6-membered aromatic ring, X is an optionally substituted C, N or O atom, and the ring B is an optionally substituted 5- to 7-membered ring; Z is a chemical bond or a divalent group; R2 is (1) an, optionally substituted amino group in which a nitrogen atom may form a quaternary ammonium, etc., or a salt thereof, which is useful for antagonizing MCP-1 receptor.
申请公布号 US6413947(B1) 申请公布日期 2002.07.02
申请号 US20000661194 申请日期 2000.09.13
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 SHIRAISHI MITSURU;KITAYOSHI TAKAHITO;ARAMAKI YOSHIO;HONDA SUSUMU;ODA TSUNEO
分类号 C07C233/62;C07C255/25;C07D211/14;C07D211/22;C07D211/46;C07D213/20;C07D213/30;C07D213/40;C07D213/61;C07D213/68;C07D213/74;C07D213/79;C07D213/84;C07D213/85;C07D213/89;C07D223/16;C07D239/42;C07D277/22;C07D295/135;C07D307/68;C07D309/14;C07D311/58;C07D313/08;C07D317/58;C07D335/02;C07D335/06;C07D405/12;C07D405/14;C07D407/12;C07D407/14;C07D409/12;C07D409/14;C07D453/02;C07D521/00;C07F9/44;C07F9/53;C07F9/54;C07F9/655;C07F9/6568;C07F9/6584;(IPC1-7):A61K31/452;A61K31/445;C07D295/12;C07D333/36 主分类号 C07C233/62
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