发明名称 Powder preparations containing hydroxypyridones; useful for treating leg ulcers and/or decubitus ulcers
摘要 The use of a powder comprising at least one 1-hydroxy-2-pyridone of the formula (I), wherein: R1, R2 and R3, which are identical or different, are H or alkyl with 1-4 carbon atoms; R4 is a saturated hydrocarbon radical with 6 to 9 carbon atoms or a radical of formula (II), wherein: X is S or O; Y is H or up to 2 halogen atoms such as chlorine and/or bromine; Z is a single bond or the divalent radicals O, S, -CR2-, in which R is H or (C1-C4)-alkyl, or other divalent radicals with 2-10 carbon atoms and, where appropriate, O and/or S atoms linked in the form of a chain, it being necessary - if the radicals contain 2 or more O and/or S atoms - for the latter to be separated from one another by at least 2 carbon atoms, and it also being possible for 2 adjacent carbon atoms to be linked together by a double bond, and the free valencies of the C atoms being saturated by H and/or (C1-C4)-alkyl groups; Ar is an aromatic ring system which has up to two rings and which may be substituted by up to three radicals from the group of fluorine, chlorine, bromine, methoxy, (C1-C4)-alkyl, trifluorormethyl and trifluoromethoxy, for the production of a pharmaceutical for the treatment of leg ulcers and/or decubitus ulcers.
申请公布号 NZ505898(A) 申请公布日期 2002.06.28
申请号 NZ19990505898 申请日期 1999.01.11
申请人 AVENTIS PHARMA DEUTSCHLAND GMBH 发明人 BOHN, MANFRED;KRAEMER, KARL THEODOR
分类号 C07D213/89;A61K9/00;A61K9/14;A61K31/44;A61K31/4412;A61K31/4418;A61K47/04;A61K47/26;A61K47/36;A61P17/02;(IPC1-7):A61K31/441;A61K31/441 主分类号 C07D213/89
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