发明名称 |
QUINAZOLINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESSES FOR PREPARING THEM |
摘要 |
The invention relates to quinazoline derivatives of general formula (I), wherein R~a, R~b and R~c have the meaning defined in claim 1, to their tautomers, their stereoisomers and their salts, especially their physiologically acceptable salts with inorganic or organic acids. Said compounds have valuable pharmacological properties, especially an inhibiting effect upon signal transduction caused by tyrosine kinase. The invention further relates to their utilization in the treatment of diseases, especiall y of tumoral diseases, diseases of the lung and the respiratory tract and to t he production of said compounds.
|
申请公布号 |
CA2432428(A1) |
申请公布日期 |
2002.06.27 |
申请号 |
CA20012432428 |
申请日期 |
2001.12.12 |
申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
LANGKOPF, ELKE;BLECH, STEFAN;BAUM, ANKE;JUNG, BIRGIT;HIMMELSBACH, FRANK;SOLCA, FLAVIO |
分类号 |
A61K31/517;A61K31/5377;A61P1/00;A61P1/04;A61P1/16;A61P11/00;A61P11/06;A61P11/08;A61P17/06;A61P27/16;A61P29/00;A61P35/00;A61P35/04;A61P37/02;A61P37/08;A61P43/00;C07D239/94;C07D405/12;(IPC1-7):C07D239/94;A61K31/505 |
主分类号 |
A61K31/517 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|