BIOLOGICALLY ACTIVE AGENT DELIVERY APPARATUS AND METHOD

摘要

A prosthesis (122), for use within a hollow body structure of a patient, comprises a coiled body (105) having a radially-extending openings (113), the coiled body being movable from a radially-contracted state to a radially-expanded state. A material (124) extends along a coiled path algon the coiled body. A dispensable, biologically active agent (M, 147) is associated with at least one of the coiled body and material. The material may comprise a coiled sleeve of material having inner and outer surfaces (124B, 124A), the inner surface defining a sleeve interior (124C) containing the coiled body. The dispensable agent may be, for example, on the outer surface of the material, incorporated into the material to create an agent/material matrix, or on the inner surface of the material or within the sleeve interior. Structure may be used to delay the migration of the agent to the patient.