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发明名称
含醯胺及视网醇之护肤组合物
摘要
具特定结构之N-取代脂肪酸醯胺可充分抑制视网醇经 LRAT或ARAT催化之酯化作用、而转化为非活化视网酯之化合物,视网醇或视网酯掺合此等具特定结构之N-取代脂肪酸醯胺之功效,系类似于经视网酸处理之效果。
申请公布号
TW491706
申请公布日期
2002.06.21
申请号
TW086118982
申请日期
1997.12.16
申请人
联合利华公司
发明人
史都华派顿葛兰格;安东尼文森洛林;艾恩理察史考特
分类号
A61K7/02
主分类号
A61K7/02
代理机构
代理人
陈长文 台北巿敦化北路二○一号七楼
主权项
1.一种护肤组合物,其包含:(a)自0.001%至10%之视网醇;(b)自0.0001%至50%之N-取代脂肪酸醯胺,其具下列结构:其中R1=具1至10个碳原子之烷基或烷氧基;R2=具8至25个碳原子之烷基或烯基;R3=具1至5个碳原子之烷基,或磷酯,其中该N-取代脂肪酸醯胺系经由活体外微粒体测定显示于100M之浓度下、可抑制至少20%的由LRAT或ARAT催化之视网酯化反应者;以及(c)一种化妆品可接受媒液。
地址
荷兰
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