MOLECULE CORRESPONDENT TO GENOTYPE AND PHENOTYPE, COMPOSING ELEMENTS THEREOF, METHOD OF PRODUCING THE CORESPONDENT MOLECULE AND METHOD OF USING THE SAME

摘要

A correspondent molecule wherein: (a) a spacer molecule containing a donor region capable of binding to the 3'-terminus of a nucleic acid, a PEG region mainly comprising polyethylene glycol which is bonded to the donor region, and a peptide acceptor region containing a group capable of binding to a peptide by transpeptidation which is bonded to the PEG region, and (b) a genotype molecule having a 5'-nontranslational region containing a transcriptional promoter and a translational enhancer, an ORF region encoding a protein which is bonded in the 3'-side of the 5'-nontranslational region, and the 3'-end of a code molecule which is a nucleic acid containing the 3'-terminal region containing a polyA sequence which is bonded in the 3'-side of the ORF region, are ligated to a phenotype molecule, which is a protein encoded by the ORF region in the genotype molecule, via transpeptidation.