ATTENUATED HUMAN'S ROTAVIRUS COMPOSITION, ROTAVIRUS AND VACCINE COMPOSITION, WHICH CONTAINS ALIVE ATTENUATED HUMAN'S ROTAVIRUS

摘要

The invention provides an attenuated rotavirus population comprising a single variant or substantially a single variant, which is defined by a nucleotide sequence encoding at least one of the major viral proteins designated as VP4 and VP7. The invention particularly provides a rotavirus population designated as P43 and deposited under accession number ECACC 99081301. The invention further provides a novel formulation for a rotavirus vaccine, which is in the form of a quick dissolving tablet for immediate dissolution when placed on the tongue.