| 发明名称 |
PROJECTION AGAINST MYCOBACTERIAL INFECTIONS |
| 摘要 |
The present invention relates to a method of identifying mycobacterial genes which wre induced or up-regulated during <i>M. tuberculosis</i> virulence, and to isolated peptide products of said genes. Also provided, are inhibitors of said genes, and antibodies which bind to said peptide products. Further embodiments include DNA and RNA vectors encoding said products, attenuated mycobacteria in which the activity of at least one of said genes or peptide products has been modified, vaccines against mycobacterial infections, and methods of detecting a mycobacterial infection. |
| 申请公布号 |
WO0244406(A2) |
申请公布日期 |
2002.06.06 |
| 申请号 |
WO2001GB05250 |
申请日期 |
2001.11.28 |
| 申请人 |
MICROBIOLOGICAL RESEARCH AUTHORITY CAMR;VIPOND, RICHARD;SHUTTLEWORTH, HELEN;AMBROSE, EMMA;MINTON, NIGEL, PETER |
发明人 |
VIPOND, RICHARD;SHUTTLEWORTH, HELEN;AMBROSE, EMMA;MINTON, NIGEL, PETER |
| 分类号 |
C12N15/09;A61K38/00;A61K39/00;A61K39/04;A61K39/395;A61K48/00;A61P31/04;A61P31/06;A61P43/00;C07K14/35;C07K16/12;C12N1/21;C12N7/00;C12N15/31;C12N15/74;C12P21/02;C12Q1/02;C12Q1/68;C12R1/32 |
主分类号 |
C12N15/09 |
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