发明名称 |
INDANYL-SUBSTITUTED BENZOLE CARBONAMIDE, METHOD FOR THE PRODUCTION OF THE SAME, USE THEREOF AS A MEDICAMENT AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME |
摘要 |
<p>in which R(1) to R(8) have the meanings stated in the claims, act on the Kv1.5 potassium channel, and inhibit a potassium current, referred to as "ultra-rapidly activating delayed rectifier," in the human atrium. They are therefore very particularly suitable as novel antiarrhythmic active substances, in particular for the treatment and prophylaxis of atrial arrhythmias, e.g., atrial fibrillation or atrial flutter.</p> |
申请公布号 |
SK19092001(A3) |
申请公布日期 |
2002.06.04 |
申请号 |
SK20010001909 |
申请日期 |
2000.06.10 |
申请人 |
AVENTIS PHARMA DEUTSCHLAND GMBH |
发明人 |
BRENDEL JOACHIM;GERLACH UWE;STILZ HANS ULRICH;LANG HANS JOCHEN |
分类号 |
C07D295/22;A61K31/18;A61K31/4453;A61K31/472;A61K31/5375;A61P9/06;C07C303/40;C07C311/16;C07C311/20;C07C311/21;C07C311/26;C07C311/29;C07C311/39;C07D217/02;C07D295/26;(IPC1-7):C07C311/16;A61K31/445 |
主分类号 |
C07D295/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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