发明名称 |
HOUTTUYNINUM COMPOSITIONS AND METHODS FOR INHIBITING THE ACTIVITY OF ERBB-2 BASED THEREON |
摘要 |
The present invention relates to methods and compositions for inhibiting the activity of erbB-2. The described methods and compositions are particularly useful for inhibiting cellular proliferative disorders, such as cancer, characterized by over-activity and/or inappropriate activity of erbB-2. More particularly, method for the treatment of a cellular proliferative disorder characterized by over-activity or inappropriate activity of erbB-2 is provided including the step of administering to a patient in need of such treatment a therapeutically effective amount of soluble extract of houttuynum, or a compound selected from the group consisting of houttuyninum, Houttuymia cordata, neo-houttuyninum (decanoyl acetaldehyde), analogs thereof, pharmaceutically acceptable salts thereof, and/or prodrugs thereof. |
申请公布号 |
WO0241828(A2) |
申请公布日期 |
2002.05.30 |
申请号 |
WO2001US43123 |
申请日期 |
2001.11.19 |
申请人 |
YANG, DAJUN;ZHU, XIAO, F.;WANG, JINGSON;ZENG, YIXING |
发明人 |
YANG, DAJUN;ZHU, XIAO, F.;WANG, JINGSON;ZENG, YIXING |
分类号 |
A61K;A61K31/10;A61K31/12;A61K36/185 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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