发明名称 |
POLYCYCLIC XANTHONES AS ANTIBIOTICS |
摘要 |
A novel class of antitumour compounds has been recognised based on the isolation from a new marine microbe, strain PO13-046, belonging to the genus <i>Actinomadura sp.</i>), of a compound designated IB-00208. The class of the formulae (I) or (II) where R<1> can be hydrogen, acyl, alkyl, alkenyl, aryl, benzyl, alkali metal, and/or sugar, and R<2> and R<3> can be hydrogen, alkyl, or together R<2> and R<3> form an unsaturated bond. Such compounds demonstrate an interesting activity several cancel cell lines and against Gram-positive bacteria. |
申请公布号 |
WO0200663(A3) |
申请公布日期 |
2002.05.30 |
申请号 |
WO2001GB02898 |
申请日期 |
2001.06.29 |
申请人 |
INSTITUTO BIOMAR S.A.;RUFFLES, GRAHAM, KEITH;PEREZ-BAZ, JULIA;CANEDO, LIBRADA, MARIA;GARCIA GRAVALOS, DOLORES;ROMERO, FRANCISCO;ESPLIEGO, FERNANDO |
发明人 |
PEREZ-BAZ, JULIA;CANEDO, LIBRADA, MARIA;GARCIA GRAVALOS, DOLORES;ROMERO, FRANCISCO;ESPLIEGO, FERNANDO |
分类号 |
A61K31/366;A61P31/04;A61P35/00;C07D493/04;C07H17/08;C12N1/20;C12P17/18;C12P19/60;C12R1/03 |
主分类号 |
A61K31/366 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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