Impfstoffe, die rekombinante Hantavirusproteine enthalten, Verfahren zu iher Herstellung und ihre Verwendung

摘要

The invention relates to vaccines against hantaviruses, to methods for producing said vaccines and to their use. The scope of application is medicine or veterinary medicine. The invention is characterised by the use of a yeast high-expression system, which enables large quantities of recombinant hantavirus proteins to be obtained. The recombinant proteins are purified by density gradient centrifugation or affinity chromatography. Obtaining the proteins from yeast cells ensures that they are free of endotoxins and suitable for human applications as vaccines and in the development of diagnostics.