METHOD FOR ESTIMATING METABOLIC FUNCTION OF XENOBIOTIC AND INDUCTION THEREOF

摘要

Thawed Cryopreserved primary human hepatocytes are maintained in a serum-free synthetic medium containing glucocorticoid, and they are made to contact with a test compound, thereby enabling stable implementation of estimation of metabolic function of xenobiotics and induction thereof, using human hepatocyte retaining the traits for differentiation.