| 摘要 |
The present invention provides an apparatus and a method for producing a virtual electrode within or upon a tissue to be treated with radio frequency alternating electric current, such tissues including but not limited to brain, liver, cardiac, prostate, breast, and vascular tissues and neoplasms. An apparatus in accordance with the present invention includes a source of super-cooled fluid for selectively providing super-cooled fluid to the target tissue to cause a temporary cessation of cellular or electrical activity, a supply of conductive or electrolytic fluid to be provided to the target tissue, and alternating current generator, and a processor for creating, maintaining, and controlling the ablation process by the interstitial or surficial delivery of the fluid to a tissue and the delivery of electric power to the tissue via the virtual electrode. A method in accord with the present invention includes delivering super-cooled fluid to the target tissue to cause a temporary cessation of cellular or electrical activity, evaluating whether the temporary cessation of cellular or electrical activity is the desired cessation of cellular or electrical activity, and if so, delivering a conductive fluid to the predetermined tissue ablation site for a predetermined time period, applying a predetermined power level of radio frequency current to the tissue, monitoring at least one of several parameters, and adjusting either the applied power and/or the fluid flow in response to the measured parameters.
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