| 发明名称 |
Sulfamatohydrxamic acid functioning as inhibitor of metalloproteases |
| 摘要 |
<p>A sulfamato hydroxamic acid compound that inter alia inhibits matrix metalloprotease activity is disclosed as are a process for preparing the same, intermediate compounds useful in those syntheses, and a treatment process that comprises administering a contemplated sulfamato hydroxamic acid compound in a MMP enzyme-inhibiting effective amount to a host having a condition associated with pathological matrix metalloprotease activity.</p> |
| 申请公布号 |
CZ20012849(A3) |
申请公布日期 |
2002.05.15 |
| 申请号 |
CZ20010002849 |
申请日期 |
2000.02.07 |
| 申请人 |
G. D. SEARLE & CO. CORPORATE PATENT DEPT. |
发明人 |
DE CRESCENZO GARY A.;RICO JOSEPH G.;BOEHM TERRI L.;CARROLL JEFFERY N.;KASSAB DARREN J.;MISCHKE DEBORAH A. |
| 分类号 |
C07D491/113;A61K;A61K31/4025;A61K31/423;A61K31/427;A61K31/445;A61K31/453;A61K31/454;A61K31/4545;A61K31/496;A61P;A61P1/02;A61P1/04;A61P7/02;A61P9/00;A61P13/12;A61P17/00;A61P19/00;A61P19/02;A61P25/28;A61P27/02;A61P29/00;A61P35/00;A61P35/04;C07D;C07D207/48;C07D211/46;C07D211/66;C07D211/96;C07D295/26;C07D309/08;C07D309/10;C07D401/12;C07D401/14;C07D403/12;C07D405/12;C07D405/14;C07D409/12;C07D409/14;C07D413/12;C07D413/14;C07D417/12;C07D417/14;C07D471/08;C07D491/10;(IPC1-7):C07D405/12 |
主分类号 |
C07D491/113 |
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