| 发明名称 |
Sulfamides as gamma-secretase inhibitors |
| 摘要 |
Novel sulfamides of formula (I) are disclosed. The compounds exert an inhibitory action on the processing of APP by gamma-secretase, and are therefore useful in the treatment or prevention of Alzheimer's disease. |
| 申请公布号 |
AU1074702(A) |
申请公布日期 |
2002.05.15 |
| 申请号 |
AU20020010747 |
申请日期 |
2001.10.29 |
| 申请人 |
MERCK SHARP AND DOHME LIMITED |
发明人 |
IAN JAMES COLLINS;JOANNE CLAIRE HANNAM;TIMOTHY HARRISON;STEPHEN JOHN LEWIS;ANDREW MADIN;TIMOTHY JASON SPAREY;BRIAN JOHN WILLIAMS |
| 分类号 |
C07D295/08;A61K31/145;A61K31/18;A61K31/40;A61K31/4245;A61K31/433;A61K31/439;A61K31/4439;A61K31/445;A61K31/454;A61K31/496;A61K31/497;A61K31/4985;A61K31/5375;A61K31/5377;A61K31/5386;A61K31/549;A61P25/28;A61P43/00;C07C307/02;C07C307/08;C07C311/07;C07C311/09;C07C311/11;C07C311/14;C07C311/20;C07C311/24;C07C323/67;C07D207/36;C07D211/14;C07D211/18;C07D213/30;C07D213/71;C07D213/81;C07D215/12;C07D223/32;C07D271/10;C07D271/107;C07D277/36;C07D285/14;C07D285/16;C07D285/20;C07D295/092;C07D295/12;C07D295/135;C07D295/26;C07D307/64;C07D307/81;C07D319/18;C07D333/34;C07D409/12;C07D413/12;C07D413/14;C07D417/04;C07D417/06;C07D417/12;C07D417/14;C07D487/04;C07D487/08;C07D491/08;C07D491/10;C07D513/10;C07D521/00 |
主分类号 |
C07D295/08 |
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