| 摘要 |
Process for preparing optically (S) and (R) active amines of the formula (I*)comprising reacting racemic amines corresponding to formula (I*) with esters of the formula:in the presence of lipase from Candida antarctica, and separating the (S)-amine directly from the resulting mixture, and separating the (R)-amine indirectly from the resulting mixture by reacting the acylated (R)-amine therein, which has the formula:with acid or base, wherein all the formula above, the variables are as defined herein. Certain precursors of the formula (III) are also disclosed.
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