| 发明名称 |
EPITOPE-BETA MICROGLOBULIN POLYNUCLEOTIDE FOR ANTI-CANCER IMMUNOTHERAPY |
| 摘要 |
<p>The present invention relates to polynucleotides for use in cancer therapy. In particular, the invention provides a polynucleotide capable of expressing an epitope-.beta.2m fusion protein; for use in the generation of cytotoxic T lymphocyte (CTL) responses against a tumour; and a polynucleotide capable of expressing an epitope-.beta.2m fusion protein; for use in a method of restoring antigen presentation in the tumour of a host.</p> |
| 申请公布号 |
CA2463623(A1) |
申请公布日期 |
2002.05.10 |
| 申请号 |
CA20012463623 |
申请日期 |
2001.11.01 |
| 申请人 |
ISIS INNOVATION LIMITED |
发明人 |
MCMICHAEL, ANDREW JAMES;HUNTER, MICHAEL;BELL, JOHN IRVING;LAYTON, GUY;MEIER, UTE-CHRISTIANE;TAFURO, SABRINA |
| 分类号 |
A61K35/56;A61K38/00;A61P31/12;A61P35/00;C07K14/11;C07K14/74;(IPC1-7):A61K38/16;A61K39/00;C12N15/12;C12N15/62 |
主分类号 |
A61K35/56 |
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