发明名称 Pseudopeptide compounds having an inhibiting activity with respect to paths activated by proteins with active tyrosine kinase activity and pharmaceutical compositions containing same
摘要 The invention concerns a compound corresponding to general formula (1) wherein, in particular, R2 represents a phenylmethyl or naphthylmethyl or cyclohexylmethyl radical, 2- and 3-pryidinylmethyl, substituted on the cycle in meta or para position by an acid group or an alkyl radical of the type (CH2)n (with n=3 or 4) substituted in terminal position by an acid group; and R3 represents a hydrogen group or a linear or branched C1-C4 alkyl or alkylcycloalkyl with a C3-C6 cycloalkyl. The invention also concerns the use of a compound of general formula (I) for preparing a pharmaceutical composition for treating diseases related to proliferative processes, cancers and/or metastases.
申请公布号 US2002055463(A1) 申请公布日期 2002.05.09
申请号 US20010977349 申请日期 2001.10.16
申请人 GARBAY CHRISTIANE;LIU WANG-QING;VIDAL MICHEL;ROQUES BERNARD P. 发明人 GARBAY CHRISTIANE;LIU WANG-QING;VIDAL MICHEL;ROQUES BERNARD P.
分类号 A61K38/00;C07K5/02;C07K5/08;C07K14/71;(IPC1-7):A61K38/06 主分类号 A61K38/00
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