发明名称 Spiro compounds or salts thereof and preventives/remedies for autoimmune diseases and AP-1 inhibitors containing the same
摘要 The spiro compounds of the present invention represented by the general formula:wherein A, R2, R3, R4, R5, R6 and n are as defined in the specification, exhibit an AP-1 activity inhibitory action and, based on the AP-1 inhibitory action, suppresses the expression of a wide variety of genes and are useful as an agent for treating and preventing autoimmune diseases with lessoned side reactions.
申请公布号 US6384065(B1) 申请公布日期 2002.05.07
申请号 US20000674483 申请日期 2000.11.08
申请人 TOYAMA CHEMICAL CO., LTD. 发明人 CHAKI HISAAKI;AIKAWA YUKIHIKO;MIYAJIMA MIKAKO;NISHIO MORIHIRO;KURODA HIROSHI;TANAKA KEIICHI;HIRONO SHUICHI;SHIOZAWA SHUNICHI
分类号 A61K38/00;C07D277/60;C07D417/04;C07D417/06;C07D417/08;C07D417/12;C07D513/10;C07K5/078;(IPC1-7):A61K31/426 主分类号 A61K38/00
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