发明名称 Fast disintegrating tablet.
摘要 The invention concerns an improved multiparticulate tablet disintegrating in the mouth in contact with saliva in less than 40 seconds. The invention is characterized in that it is based on particles of coated active principle, said particles having intrinsic compression properties and a mixture of carriers, the proportion of carrier mixture relative to coated active principle particles being 0.4 to 6 parts by weight, the carrier mixture comprising: a disintegrating agent; a diluting soluble agent with binding properties; a lubricant; a permeabilizing agent; and advantageously lubricants, sweeteners, flavoring and coloring agents, the proportion of disintegrating agent and soluble agent relative to the tablet mass being 1 to 15 wt. % for the former and 30 to 90 wt. % for the latter.
申请公布号 ZA200103629(B) 申请公布日期 2002.05.06
申请号 ZA20010003629 申请日期 2001.05.04
申请人 LABORATOIRES DES PRODUITS ETHIQUES ETHYPHARM SA. 发明人 CHARLES ANDRE CHAUVEAU;JEAN-MARC ZUCCARELLI;NOURREDINE NOURI;MARYVONNE BARBERO
分类号 A61K47/10;A61K9/00;A61K9/20;A61K9/26;A61K31/167;A61K31/192;A61K31/616;A61K47/04;A61K47/12;A61K47/14;A61K47/26;A61K47/32;A61K47/34;A61K47/36;A61K47/38;A61K47/40;A61K47/42 主分类号 A61K47/10
代理机构 代理人
主权项
地址