发明名称 AGENT FOR PREVENTING OR TREATING PORTAL HYPERTENSION
摘要 Preventives/remedies for portal hypertension containing compounds represented by the general formula (I), salts thereof or prodrugs of the same are provided. In said formula, R1 represents a group capable of forming an anion; X represents a bond or a spacer; n is an integer of 1 or 2; the ring A is an optionally substituted benzene ring; R2 represents a group capable of forming an anion; and R3 represents optionally substituted hydrocarbyl which may bonded via a hetero atom. These drugs are sufficiently excellent as medicines, since they have favorable preventive and therapeutic effects on portal hypertension without any side effect.
申请公布号 CA2426674(A1) 申请公布日期 2002.05.02
申请号 CA20012426674 申请日期 2001.10.24
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 WATANABE, TOSHIFUMI;KUSUMOTO, KEIJI;OJIMA, MAMI
分类号 A61K9/16;A61K9/20;A61K9/48;A61K31/4164;A61K31/4178;A61K31/4184;A61K31/4245;A61K31/433;A61P9/12;A61P43/00;C07D403/10;(IPC1-7):A61K31/41;A61K45/00;C07D401/10;C07D413/10;C07D417/10;A61K31/417;A61K31/418;A61K31/424 主分类号 A61K9/16
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