| 发明名称 |
NOVEL AGGRECANASE MOLECULES |
| 摘要 |
Aggrecanase proteins and the nucleotides sequences encoding them as well as processes for producing them are disclosed. Methods for developing inhibitor s of the aggrecanase enzymes and antibodies to the enzymes for treatment of conditions characterized by the degradation of aggrecan are also disclosed.< /SDOAB>
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| 申请公布号 |
CA2426463(A1) |
申请公布日期 |
2002.05.02 |
| 申请号 |
CA20012426463 |
申请日期 |
2001.10.17 |
| 申请人 |
GENETICS INSTITUTE, LLC |
发明人 |
RACIE, LISA ANNE;TWINE, NATALIE CONSTANCE;WOLFMAN, NEIL MICHAEL;AGOSTINO, MICHAEL JOHN;MORRIS, ELISABETH ANN |
| 分类号 |
C12N15/09;A61K38/00;A61K39/395;A61P19/02;A61P43/00;C07K16/40;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/48;C12N9/50;C12N9/64;(IPC1-7):C12N9/64;C12N15/52 |
主分类号 |
C12N15/09 |
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