发明名称 |
Multiplexing methods for identifying nucleic acids using denaturing liquid chromatography |
摘要 |
A method is provided for the separation of nucleic acid samples. The method includes: providing a test mixture of a plurality of nucleic acid samples, wherein each sample is labeled with a spectrally detectable tag; applying the test mixture to a reversed phase solid support; eluting the mixture under partially denaturing conditions; and detecting spectrally resolved signals produced by the nucleic acid samples labeled with the detectable tags.
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申请公布号 |
US6379889(B1) |
申请公布日期 |
2002.04.30 |
申请号 |
US19990434035 |
申请日期 |
1999.11.04 |
申请人 |
AGILENT TECHNOLOGIES, INC. |
发明人 |
APFFEL, JR. JAMES A.;HAHNENBERGER KAREN M.;KRONICK MEL N.;VERHOEF MARTIN |
分类号 |
C12Q1/68;(IPC1-7):C12Q1/68;G01N33/00;C07H21/02 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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