发明名称 |
METHODS OF AND COMPOSITIONS FOR POTENTIATING THE ACTION OF AGENTS ACTIVE ON CELL WALL SITES OF THE SUSCEPTIBLE BACTERIA |
摘要 |
The invention provides a method of potentiating the activity of antibacterial agents that act on bacterial cell walls, comprising the step of administering to a subject an antibacterial agent and an aminoglycoside to attain a peak concentration of at least 4 mg/l of aminoglycoside and thereafter maintaining the aminoglycoside at a concentration of up to 4 mg/l for at least 1 hour. Compositions comprising an antibacterial agent and an aminoglycoside for efficacious treatement of bacterial infection are also provided.
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申请公布号 |
US2002049171(A1) |
申请公布日期 |
2002.04.25 |
申请号 |
US19980117105 |
申请日期 |
1998.08.26 |
申请人 |
MCLEAN ALLAN JOSEPH |
发明人 |
MCLEAN ALLAN JOSEPH |
分类号 |
C07H15/234;A01N43/04;A61K31/00;A61K31/545;A61K31/546;A61K31/70;A61K31/7028;A61K31/7034;A61K31/7036;A61K45/06;A61P31/00;A61P31/04;C07G11/00;C07H15/20;C07H15/22;C07H15/236;C07H15/238;(IPC1-7):C07H15/20 |
主分类号 |
C07H15/234 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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