发明名称 NON-DELIQUESCENT SALT OF 4-HYDROXYPIPERIDINE DERIVATIVE
摘要 A non-deliquescent salt of a 4-hydroxypiperidine derivative represented by the following formula (I) or a solvate thereof. In said formula, Q represents thienylmethyl or 4-cyanophenylethyl; A represents methylene or ethylene; R represents hydrogen or methyl; n is 1 or 2; Z represents an acid selected from the group consisting of hydrochloric acid, hydrobromic acid, hydriodic acid, oxalic acid, malic acid, tartaric acid, citric acid, benzenesulfonic acid, and toluenesulfonic acid; and when n is 2, then Zs may be the same or different, provided that the case where R is methyl, n is 2, and Z hydrochloric acid is excluded. Also provided is a medicinal composition containing the non-deliquescent salt or solvate as the active ingredient.
申请公布号 WO0230900(A1) 申请公布日期 2002.04.18
申请号 WO2001JP08571 申请日期 2001.09.28
申请人 MOCHIDA PHARMACEUTICAL CO., LTD.;MATSUURA, KAZUYUKI;SUZUKI, KAZUHIRO 发明人 MATSUURA, KAZUYUKI;SUZUKI, KAZUHIRO
分类号 C07D409/06;A61K31/4433;A61K31/4535;A61P9/06;A61P9/08;C07D211/48;(IPC1-7):C07D211/48;A61K31/445;A61K31/453;A61K9/06 主分类号 C07D409/06
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